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Lookup NU author(s): Professor Francisco FigueiredoORCiD
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Copyright © 2021 Published by Wolters Kluwer on behalf of ASCRS and ESCRS.PURPOSE: To analyze real-world graft survival and visual acuity outcomes of corneal transplantation in Europe. SETTING: Corneal clinics in 10 European Union member states, the United Kingdom, and Switzerland. DESIGN: Multinational registry study. METHODS: All corneal transplant procedures registered in the European Cornea and Cell Transplantation Registry (ECCTR) were identified. Graft survival of primary corneal transplants were analyzed using Kaplan-Meier survival curves with log-rank test and Cox regression. Corrected distance visual acuities (CDVAs) are reported at baseline and 2 years postoperatively using the Lundström distribution matrix. RESULTS: A total of 12 913 corneal transplants were identified. Overall, 32-year graft survival of corneal transplants was high (89%) but differed between indications, ranging from 98% in keratoconus and 80% for trauma. Overall, CDVA improved postoperatively, but the risk for losing vision ranged from 7% (baseline vision ≤0.1 Snellen) to 58% (baseline vision ≥1.0 Snellen). CONCLUSIONS: This report provides a comprehensive overview of graft survival and visual outcomes of corneal transplantation in Europe. In addition, it provides real-world estimates of outcomes for a variety of indications and surgical techniques to support benchmarking and demonstrates the relationship between baseline and postoperative vision.
Author(s): Dunker SL, Armitage WJ, Armitage M, Brocato L, Figueiredo FC, Heemskerk MBA, Hjortdal J, Jones GLA, Konijn C, Nuijts RMMA, Lundstrom M, Dickman MM
Publication type: Article
Publication status: Published
Journal: Journal of Cataract and Refractive Surgery
Year: 2021
Volume: 47
Issue: 6
Pages: 780-785
Online publication date: 01/06/2021
Acceptance date: 02/04/2021
ISSN (print): 0886-3350
ISSN (electronic): 1873-4502
Publisher: Wolters Kluwer
URL: https://doi.org/10.1097/j.jcrs.0000000000000520
DOI: 10.1097/j.jcrs.0000000000000520
PubMed id: 33278237
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