Browse by author
Lookup NU author(s): Professor Sanjay PandanaboyanaORCiD
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
© 2014 International Hepato-Pancreato-Biliary Association.Introduction Delayed gastric emptying (DGE) is a common complication after a pylorus-preserving pancreatoduodenectomy (PPPD) and is associated with significant morbidity. This study determines whether DGE is affected by antecolic (AC) or retrocolic (RC) reconstruction after a PPPD. Method An electronic search was performed of the MEDLINE, EMBASE and PubMed databases to identify all articles related to this topic. Pooled risk ratios (RR) were calculated for categorical outcomes, and mean differences (MD) for secondary continuous outcomes using the fixed-effects and random-effects models for meta-analysis. Results Nine studies including 878 patients met the inclusion criteria. DGE was lower with an AC reconstruction RR 0.31 [0.12, 0.78] Z = 2.47 (P = 0.010). Length of stay (LOS) MD -4 days [-7.63, -1.14] Z = 2.65 (P = 0.008) and days to commence a solid diet MD -5 days [-6.63, -3.15] Z = 5.50 (P ≤ 0.000) were also significantly in favour of the AC group. There was no difference in the incidence of pancreatic fistula, intra-abdominal collection/bile leak or mortality between the two groups. Conclusion AC reconstruction after PPPD is associated with a lower incidence of DGE. Time to oral intake was significantly shorter with AC reconstruction, with a reduced hospital stay.
Author(s): Bell R, Pandanaboyana S, Shah N, Bartlett A, Windsor JA, Smith AM
Publication type: Review
Publication status: Published
Journal: HPB
Year: 2015
Volume: 17
Issue: 3
Pages: 202-208
Print publication date: 01/03/2015
Acceptance date: 28/08/2014
ISSN (print): 1365-182X
ISSN (electronic): 1477-2574
Publisher: Blackwell Publishing Ltd
URL: https://doi.org/10.1111/hpb.12344
DOI: 10.1111/hpb.12344
PubMed id: 25267428
