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Lookup NU author(s): Professor Sanjay PandanaboyanaORCiD
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© 2016 Royal Australasian College of Surgeons.Background: The need for an early determination of resectability and before an irreversible step is taken during pancreatoduodenectomy promoted the development of an 'artery first approach' (AFA). The aim of this study was to review the current evidence related to this approach, with particular reference to margins and survival. Methods: An electronic search was performed in MEDLINE, EMBASE and PubMed databases from 1960 to 2015 using both subject headings (MeSH) and truncated word searches to identify all published related articles to this topic. Results: Six different AFAs have been published. Four studies evaluated the impact of AFA on perioperative outcomes and survival. Three studies showed no difference in the perioperative outcomes, margin status, lymph node yield and survival while one study showed improved margin status and survival comparing AFA with standard resection. Conclusion: The current evidence regarding the benefits of AFA in relation to decreasing margin positivity or increasing survival is sparse. Further larger studies and randomized controlled trails are needed to ascertain the benefits of AFA.
Author(s): Pandanaboyana S, Bell R, Windsor J
Publication type: Review
Publication status: Published
Journal: ANZ Journal of Surgery
Year: 2016
Volume: 86
Issue: 3
Pages: 127-132
Print publication date: 03/03/2016
Online publication date: 05/08/2015
Acceptance date: 01/06/2015
ISSN (print): 1445-1433
ISSN (electronic): 1445-2197
Publisher: Blackwell Publishing
URL: https://doi.org/10.1111/ans.13249
DOI: 10.1111/ans.13249
PubMed id: 26246127