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Lookup NU author(s): Professor Sanjay PandanaboyanaORCiD
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© 2016 Royal Australasian College of Surgeons.Background: There is conflicting evidence regarding whether streamlining of blood flow within the portal vein influences the anatomical distribution of colorectal liver metastases (CRLM). This study assesses the relationship between primary tumour location and metastases location. Methods: Patients were identified using a prospectively maintained database, and those with known site of primary colorectal tumour and hemiliver involvement were included. Site of metastases and segments affected were confirmed via review of the radiology reports. The location of primary colonic tumour was confirmed via review of clinical correspondence letters. Results: A total of 2364 metastases were identified in 891 patients. Of these, 379 metastases were in the right lobe and 156 in the left lobe, with 356 having bilobar disease. There was no significant relationship between the distribution of CRLM and the site of primary disease (left colon versus right colon) (P = 0.819). However, when the segmental location of the metastases was considered, there is a statistically significant difference between the number of right-sided CRLM compared with left-sided CRLM (P < 0.001). Conclusions: Right-sided CRLM is more likely regardless of the primary location. Portal streaming may have an effect, although the natural anatomical 'angulation', particularly of the left portal vein branch is more likely to play a role.
Author(s): Pathak S, Palkhi E, Dave R, White A, Pandanaboyana S, Prasad KR, Lodge JPA, Toogood GJ
Publication type: Article
Publication status: Published
Journal: ANZ Journal of Surgery
Year: 2016
Volume: 86
Issue: 5
Pages: 408-410
Online publication date: 14/07/2014
Acceptance date: 10/06/2014
ISSN (print): 1445-1433
ISSN (electronic): 1445-2197
Publisher: Blackwell Publishing
URL: https://doi.org/10.1111/ans.12767
DOI: 10.1111/ans.12767
PubMed id: 25040656
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