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Lookup NU author(s): Dr Gareth Parry
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© 2018, Springer International Publishing AG, part of Springer Nature. Orthotopic heart transplantation (OHT) is the “gold standard” treatment for patients with end-stage heart failure, with approximately 5000 transplants performed each year worldwide. Heart transplantation survival rates have progressively improved at all time points, despite an increase in donor and recipient age and comorbidity and greater recipient urgency; according to the registry of the International Society of Heart and Lung Transplantation (ISHLT), the median survival of patients posttransplantation is currently 12.2 years. Long-term survival is sub-optimal, and outcomes after OHT remain constrained by the development of acute rejection and cardiac allograft vasculopathy (CAV). Moreover, donor organs are in short supply, making optimal organ utilization an ongoing priority. For these reasons, substantial interest continues to exist in identifying factors portending increased survival and improved organ utilization.
Author(s): Previato M, Osto E, Kerkhof PLM, Parry G, Tona F
Publication type: Book Chapter
Publication status: Published
Book Title: Sex-Specific Analysis of Cardiovascular Function
Year: 2018
Volume: 1065
Pages: 379-388
Online publication date: 27/07/2018
Acceptance date: 02/04/2018
Series Title: Advances in Experimental Medicine and Biology
Publisher: Springer
Place Published: New York
URL: https://doi.org/10.1007/978-3-319-77932-4_24
DOI: 10.1007/978-3-319-77932-4_24
Library holdings: Search Newcastle University Library for this item
ISBN: 9783319779317