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A descriptive and broadly applicable model of therapeutic and stray absorbed dose from 6 to 25 MV photon beams

Lookup NU author(s): Dr Roger Harrison

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Abstract

© 2017 American Association of Physicists in Medicine. Purpose: To develop a simple model of therapeutic and stray absorbed dose for a variety of treatment machines and techniques without relying on proprietary machine-specific parameters. Methods: Dosimetry measurements conducted in this study and from the literature were used to develop an analytical model of absorbed dose from a variety of treatment machines and techniques in the 6 to 25 MV interval. A modified one-dimensional gamma-index analysis was performed to evaluate dosimetric accuracy of the model on an independent dataset consisting of measured dose profiles from seven treatment units spanning four manufacturers. Results: The average difference between the calculated and measured absorbed dose values was 9.9% for those datasets on which the model was trained. Additionally, these results indicate that the model can provide accurate calculations of both therapeutic and stray radiation dose from a wide variety of radiotherapy units and techniques. Conclusions: We have developed a simple analytical model of absorbed dose from external beam radiotherapy treatments in the 6 to 25 MV beam energy range. The model has been tested on measured data from multiple treatment machines and techniques, and is broadly applicable to contemporary external beam radiation therapy.

Publication metadata

Author(s): Schneider CW, Newhauser WD, Wilson LJ, Schneider U, Kaderka R, Miljanic S, Knezevic Z, Stolarcyzk L, Durante M, Harrison RM

Publication type: Article

Publication status: Published

Journal: Medical Physics

Year: 2017

Volume: 44

Issue: 7

Pages: 3805-3814

Print publication date: 07/07/2017

Online publication date: 21/04/2017

Acceptance date: 23/03/2017

ISSN (print): 0094-2405

ISSN (electronic): 2473-4209

Publisher: Wiley Blackwell

URL: https://doi.org/10.1002/mp.12286

DOI: 10.1002/mp.12286

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