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Lookup NU author(s): Professor David Leaper
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This prospective, randomised study compares a new transforming methacrylate dressing (TMD) with a silver-containing carboxymethylcellulose dressing (CMC-Ag) after application to split-thickness skin graft (STSG) donor sites. This was an unblinded, non-inferiority, between-patient, comparison study that involved patients admitted to a single-centre burn unit who required two skin graft donor sites. Each patient's donor sites were covered immediately after surgery: one donor site with TMD and the other with CMC-Ag. The donor sites were evaluated until healing or until 24 days post-application, whichever came first. Study endpoints were time to healing, daily pain scores, number of dressing changes, patient comfort and physicians' and patients' willingness to use the dressings in the future. Nineteen patients had both the dressings applied. No statistically significant difference was noted in time to healing between the two dressings (142 days using TMD compared with 132 days using CMC-Ag). When pain scores were compared, TMD resulted in statistically significantly less pain at three different time periods (2-5 days, 6-10 days and 11-15 days; P < 0001 at all time periods). Patients also reported greater comfort with TMD (P < 0001). Users rated TMD as being less easy to use because of the time and technique required for application. Reductions in pain and increased patient comfort with the use of the TMD dressing, compared with CMC-Ag, were seen as clinical benefits as these are the major issues in donor site management.
Author(s): Assadian O, Arnoldo B, Purdue G, Burris A, Skrinjar E, Duschek N, Leaper DJ
Publication type: Article
Publication status: Published
Journal: International Wound Journal
Year: 2015
Volume: 12
Issue: 3
Pages: 351-356
Print publication date: 01/06/2015
Online publication date: 06/08/2013
Acceptance date: 08/07/2013
ISSN (print): 1742-4801
ISSN (electronic): 1742-481X
Publisher: Wiley-Blackwell
URL: http://dx.doi.org/10.1111/iwj.12136
DOI: 10.1111/iwj.12136
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