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Lookup NU author(s): Professor Alison Yarnall, Professor David Deehan
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Introduction: Hip fractures can be debilitating, especially in patients with pre-existing Parkinson's disease; they have reportedly worse outcomes than non-Parkinson's disease patients.Sources of data: A computerized literature search on PubMed, Medline, Embase, and CINAHL, supplemented by a manual search of related publications.Areas of agreement: Parkinson's disease patients were found to have significantly lower bone mineral density; higher incidence of falls and hip fractures; delays to receiving their Parkinson's disease medication and surgery; higher risk of pneumonia, urinary infection, pressure sores, post-operative mortality; surgical complications and sequelae, including failed fixation, dislocation, longer hospital stay, re-operation; and increased risk of contralateral hip fracture.Areas of controversy: Regain of mobility and return to previous residential status have been variably reported.Growing points: All Parkinson's disease patients should be screened and considered for primary prevention treatment. On admission with hip fractures, attention should be paid to avoid delays to medication, ensuring safe anaesthetic and timely surgery, and post-operative chest physiotherapy and mobilization.Research: Research is needed in minimizing the bone-resorptive effects of anti-Parkinson's disease medication.
Author(s): Critchley RJ, Khan SK, Yarnall AJ, Parker MJ, Deehan DJ
Publication type: Article
Publication status: Published
Journal: British Medical Bulletin
Year: 2015
Volume: 115
Issue: 1
Pages: 135-142
Print publication date: 01/09/2015
Online publication date: 29/06/2015
Acceptance date: 12/05/2015
ISSN (print): 0007-1420
ISSN (electronic): 1471-8391
Publisher: Oxford University Press
URL: http://dx.doi.org/10.1093/bmb/ldv029
DOI: 10.1093/bmb/ldv029
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