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Lookup NU author(s): Dr Daniel Raine, Dr Philip Langley, Dr Ewen Shepherd, Dr Stephen Lord, Dr Steve Murray, Emeritus Professor Alan MurrayORCiD, Dr John Bourke
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
Background: Lead V-1 is routinely analysed due to its large amplitude AF waveform. V-1 correlates strongly with right atrial activity but only moderately with left atrial activity. Posterior lead V-9 correlates strongest with left atrial activity.Aims: (1) To establish whether surface dominant AF frequency (DAF) calculated using principal component analysis (PCA) of a modified 12-lead ECG (including posterior leads) has a stronger correlation with left atrial activity compared to the standard ECG. (2) To assess the contribution of individual ECG leads to the AF principal component in both ECG configurations.Methods: Patients were assigned to modified or standard ECG groups. In the modified ECG, posterior leads V-g and V-9 replaced V-4 and V-6. AF waveform was extracted from one-minute surface ECG recordings using PCA. Surface OAF was correlated with intracardiac DAF from the high right atrium (HRA), coronary sinus (CS) and pulmonary veins (PVs).Results: 96 patients were studied. Surface DAF from the modified ECG did not have a stronger correlation with left atrial activity compared to the standard ECG. Both ECG configurations correlated strongly with HRA, CS and right PVs but only moderately with left PVs. V-1 contributed most to the AF principal component in both ECG configurations. (C) 2015 The Authors. Published by Elsevier Ltd.
Author(s): Raine D, Langley P, Shepherd E, Lord S, Murray S, Murray A, Bourke JP
Publication type: Article
Publication status: Published
Journal: Medical Engineering & Physics
Year: 2015
Volume: 37
Issue: 2
Pages: 251-255
Print publication date: 01/02/2015
Online publication date: 22/01/2015
Acceptance date: 26/12/2014
Date deposited: 29/06/2015
ISSN (print): 1350-4533
ISSN (electronic): 1873-4030
Publisher: Elsevier
URL: http://dx.doi.org/10.1016/j.medengphy.2014.12.008
DOI: 10.1016/j.medengphy.2014.12.008
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