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Risk Factors and Screening Methods for Detecting Dementia: A Narrative Review

Lookup NU author(s): Professor Bloss Stephan

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Abstract

Accurate detection of individuals with cognitive impairment and dementia in addition to identification of those at high risk of future disease is important to guide clinical care, and has research implications regarding clinical trial recruitment and development of dementia preventative strategies. In this narrative review, we describe new proposed criteria for early diagnosis of Alzheimer's disease (AD). We also explore risk factors for dementia and evaluate methods for screening for increased risk of incident disease. We highlight variability in different diagnostic approaches. Additional work needs to be done to validate new methods across different settings (such as population-based, primary care, and memory clinics), age, and ethnic groups. Having an accurate method to assess for dementia and predict risk in routine clinical care will aid decision making and could ultimately lead to disease prevention.


Publication metadata

Author(s): Stephan BCM, Brayne C

Publication type: Review

Publication status: Published

Journal: Journal of Alzheimer's Disease

Year: 2014

Volume: 42

Issue: Supp 4

Pages: S329-S338

Print publication date: 01/01/2014

Online publication date: 26/09/2014

Acceptance date: 16/09/2014

ISSN (print): 1387-2877

ISSN (electronic): 1875-8908

Publisher: IOS PRESS

URL: http://dx.doi.org/10.3233/JAD-141413

DOI: 10.3233/JAD-141413


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