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Warfarin anticoagulation in children: is there a role for a personalized approach to dosing?

Lookup NU author(s): Dr Tina Biss, Professor Farhad Kamali

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Abstract

"Studies of children receiving warfarin have shown that body size is the major predictor of warfarin dose. However, polymorphisms in the key genes ... involved in the metabolism and action of warfarin are also responsible for a significant proportion of the interindividual variability in warfarin-dose requirement."

Publication metadata

Author(s): Biss TT, Kamali F

Publication type: Editorial

Publication status: Published

Journal: Pharmacogenomics

Year: 2012

Volume: 13

Issue: 11

Pages: 1211-1214

Print publication date: 01/08/2012

ISSN (print): 1462-2416

ISSN (electronic): 1744-8042

Publisher: Future Medicine Ltd.

URL: http://dx.doi.org/10.2217/PGS.12.92

DOI: 10.2217/PGS.12.92

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