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Lookup NU author(s): Dr Glyn NelsonORCiD
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oscillations in second-messenger signalling (e.g. calcium) have previously been shown to be important in the control of transcription. More recently, oscillations in localization and absolute levels of transcription factors and their regulators have been identified. Here we discuss the role of network motifs such as the negative feedback loop and their role in oscillatory signalling, and how oscillations in components of the nuclear factor kappaB signalling pathway are important to the dynamic control of transcription in response to a cytokine stimulus.
Author(s): Nelson DE, See V, Nelson G, White MRH
Publication type: Article
Publication status: Published
Journal: Biochemical Society Transactions
Year: 2004
Volume: 32
Issue: 6
Pages: 1090-1092
ISSN (print): 0300-5127
ISSN (electronic): 1470-8752
Publisher: Portland Press Ltd.
URL: .http//dx.doi.org/10.1042/BST0321090
DOI: 10.1042/BST0321090
Notes: Part 6 878CL Times Cited:11 Cited References Count:15
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