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Lookup NU author(s): Dr Glyn NelsonORCiD
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Our experimental data shows no correlation between NF-kappa B (ReLA) expression level and oscillation dynamics. We show that a small change to the computational model used by Barken et al. to generate their theoretical data reduces the apparent discrepancies. Cell system differences and possible compensatory changes to normal signaling in their genetically engineered knockout cells may explain differences between the two studies.
Author(s): Nelson DE, Horton CA, See V, Johnson JR, Nelson G, Spiller DG, Kell DB, White MRH
Publication type: Note
Publication status: Published
Journal: Science
Year: 2005
Volume: 308
Issue: 5718
Pages: 52
ISSN (print): 0036-8075
ISSN (electronic): 1095-9203
URL: http://dx.doi.org/10.1126/science.1108198
DOI: 10.1126/science.1108198
Notes: 914IQ Times Cited:0 Cited References Count:16