Browse by author
Lookup NU author(s): Klaas Stephan
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Diffusion tensor imaging (DTI), a magnetic resonance imaging technique, is used to infer major axonal projections in the macaque and human brain. This study investigates the feasibility of using known macaque anatomical connectivity as a "gold-standard" for the evaluation of DTI tractography methods. Connectivity information is determined from the DTI data using fast marching tractography (FMT), a novel tract-tracing (tractography) method. We show for the first time that it is possible to determine, in an entirely noninvasive manner, anatomical connection pathways and maps of an anatomical connectivity metric in the macaque brain using a standard clinical scanner and that these pathways are consistent with known anatomy. Analogous human anatomical connectivity is also presented for the first time using the FMT method, and the results are compared. The current limitations of the methodology and possibilities available for further studies are discussed. (C) 2002 Elsevier Science (USA).
Author(s): Parker GJM, Stephan KE, Barker GJ, Rowe JB, MacManus DG, Wheeler-Kingshott CAM, Ciccarelli O, Passingham RE, Spinks RL, Lemon RN, Turner R
Publication type: Article
Publication status: Published
Journal: NeuroImage
Year: 2002
Volume: 15
Issue: 4
Pages: 797-809
ISSN (print): 1053-8119
ISSN (electronic): 1095-9572
Publisher: Academic Press
URL: http://dx.doi.org/10.1006/nimg.2001.0994
DOI: 10.1006/nimg.2001.0994
Altmetrics provided by Altmetric