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Lookup NU author(s): Professor Andrew Pearson, Dr Ian Sharkey, Emeritus Professor Alan Craft
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Vomiting is one of the most distressing adverse effects of cancer chemotherapy. Metoclopramide by continuous infusion (400-mu-g/kg/h after a loading dose of 2.5 mg/kg) is a novel administration method for optimizing efficacy. A two-year-old boy developed urinary retention on three occasions, once accompanied by priapism and slurred speech, while receiving a continuous infusion. This was reversed by procyclidine, suggesting that it may have been a dystonic reaction.
Author(s): Kohli-Kumar, M., Pearson, A. D. J., Sharkey, I., Craft, A. W.
Publication type: Article
Publication status: Published
Journal: DICP-The Annals of Pharmacotherapy
Year: 1991
Volume: 25
Issue: 5
Pages: 469-470
Print publication date: 01/05/1991
ISSN (print): 0012-6578
ISSN (electronic): 1542-6270
URL: http://www.theannals.com/cgi/content/abstract/25/5/469
PubMed id: 2068829